通心络胶囊对急性冠脉综合征高敏C反应蛋白及血小板活化功能的影响

Effect of Tongxinluo Capsule on High Sensitve C Reactive Protein and Mobilizing Function of Thrombocyte

目的:探讨通心络胶囊对急性冠脉综合征患者高敏C反应蛋白(hs-CRP)、血小板胞浆内α-颗粒上的膜糖蛋白(CD62p)及溶酶体膜糖蛋白(CD63)的影响。方法:73例随机分为治疗组37例和对照组36例,两组均予常规治疗。治疗组于入院后24h内加用通心络胶囊治疗。结果:两组hs-CRP、CD62p、CD63水平,变化有极显著性差异(P<0.01),治疗4周后即可显现,8周后更为明显。结论:早期应用通心络胶囊可进一步降低急性冠脉综合征患者hs-CRP、CD62p、CD63水平。

Objective ： To approach the effect of Tongxirduo Capsule on hs- CRP, CD62p and CD63 of acute coronary syndrome patients. Method.73 cases were divided into two groups randomly,37 cases as the study group and 36 cases as the control group. Both groups were treated with conventioal therapy. The study group was treated with Tongxirduo Capsule additionally when 24 hours after hospital admission. Result： There is very significant difference in the level of hs - CRP, CD62p and CD63 between the two groups （ P 〈 0. 01 ） after 4 weeks and the difference is more obvious after 8 weeks. Conclusion ： Togxirduo Capsule used in early stage of acute coronary syndrome could lower the level of hs - CRP, CD62p and CD63.