太白盯木根皮中两个新的齐墩果酸皂苷

Two new oleanolic acid saponins from the root bark of Aralia taibaiensis

目的：对新种太白木（ＡｒａｌｉａｔａｉｂａｉｅｎｓｉｓＺ．Ｚ．ＷａｎｇｅｔＨ．Ｃ．Ｚｈｅｎｇ）根皮的皂苷成分继续进行研究。方法：利用硅胶柱层析和高效液相层析进行分离，根据皂苷的理化性质和光谱数据鉴定其结构。结果：得到３个化合物，分别确定为齐墩果酸２８ＯβＤ吡喃葡萄糖苷（Ⅰ），３ＯβＤ吡喃葡萄糖醛酸丁酯齐墩果酸２８ＯβＤ吡喃葡萄糖苷（Ⅱ）和３ＯβＤ吡喃葡萄糖醛酸癸酯齐墩果酸２８ＯβＤ吡喃葡萄糖苷（Ⅲ）。结论：皂苷Ⅱ和Ⅲ为新化合物，分别命名为太白木皂苷Ⅳ（ｔａｉｂａｉｅｎｏｓｉｄｅⅣ）和太白木皂苷Ⅴ（ｔａｉｂａｉｅｎｏｓｉｄｅⅤ），皂苷Ⅰ为首次从该植物中分得。

OBJECTIVE:To investigate the saponin constituents of the root bark of Aralia taibaiensis,a new species.METHODS:Saponins were separated by HPLC and rechromatography on silica gel,whose structures were determined by spectral analysis and chemical evidence.RESULTS:Three saponins were obtained and elucidated as oleanolic acid 28 O β D glucopyranoside(Ⅰ),3 O (6′ O butyl β D glucuronopyranosyl) oleanolic acid 28 O β D glucopyranoside(Ⅱ) and 3 O (6′ O decyl β D glucuronopyranosyl) oleanolic acid 28 O β D glucopyra noside(Ⅲ).CONCLUSION:Saponin Ⅰ was isolated from the plant for the first time.Ⅱ and Ⅲ are new compounds and named taibaienoside Ⅳ and taibaienoside Ⅴ,respectively.