摘要
采用酶联免疫法和改进微量滴定法测定３１例尿毒症患者和１２例正常人外周血肿瘤坏死因子（ＴＮＦα）和磷脂酶Ａ２（ＰＬＡ２）水平。结果显示：非透析组和单次血透后，外周血ＴＮＦα显著增高（Ｐ＜０．０１）；非透析组与腹透组血清ＰＬＡ２显著高于正常对照组（Ｐ＜０．０１）。提示血透所致急性并发症可能与ＴＮＦα升高有关；可溶性ＰＬＡ２通过血透被清除。
The levels of tumor necrosis factor a (TNFα) and phospholipase A 2 (PLA 2) in peripheral blood were determined by means of the ELISA and improved micromethod in 31 patients with urmia and 12 normal healthy persons. The results showed: ① In non dialysis group and during a single dialysis session, a significant increase in the levels of TNFα was observed. ② In non dialysis and peritoneal dialysis patients, serum levels of PLA 2 were significantly increased compared to normal subjects. The results suggest that acute complications induced by hemodialysis are related to increasing levels of TNFα, souble PLA 2 in cleared by hemodialysis.
出处
《湖南医科大学学报》
CSCD
1997年第1期78-80,共3页
Bulletin of Hunan Medical University
关键词
肾功能衰竭
TNFΑ
磷脂酶A
血液透析
尿毒症
kidney failure,chronic
tumor necrosis facor α
phospholipases A
hemodialysis
peritoneal dialysis
