影响角膜上皮下雾状混浊形成的多因素分析

MUTIPLE FACTORS ANALYSIS OF FORMATION OF CORNEAL HAZE AFTER PHOTOREFRACTIVE KERATECTOMY

采用ＶＩＳＸ２０／２０型准分子激光仪对３０６例（５２９眼）近视、散光患者进行准分子激光屈光性角膜切削术，术后观察３～１２月（８．１±３．１月）。结果显示：术后１年时高度近视眼角膜上皮下雾状混浊的发生率显著高于低、中度近视眼。影响角膜上皮下雾状混浊程度的因素有术前中央角膜厚度、术中去上皮方法及激光脉冲数等。

VISX 20/20 excimer laser was used to correct myopia from 1.00 to 16.00 diopters on 529 myopia eyes in 306 patients. All the patients were followed up for 3 to 12 months(8.1±3.1 months). At the 12th postoperative month, 0.5～3 grade corneal haze occurred in 62.1% of eyes in high myopia eyes, and only 8.8% in low and moderate myopia eyes( P <0.01). The factors of formation of the corneal haze were the central corneal thickness, methods of removing epithelium and the number of laser pulses. The results suggest that the photorefractive keratectomy is regarded safe in correction of low and moderate myopia, but not in high myopia.