急性冠脉综合征血清C-反应蛋白的临床研究

Investigation of C-reaction protein in acute coronary syndrome

目的:研究急性冠脉综合征患者血清C反应蛋白(Creaction protein,CRP)在发病中的作用及临床意义。方法:采用免疫比浊法对73例急性冠脉综合征患者的血清CRP水平进行观察,并与78例健康人进行比较。结果:急性冠脉综合征患者血清CRP浓度均高于对照组(P<0.01)。结论:急性冠脉综合征患者CRP血浆浓度升高,其升高可促进动脉粥样斑块的不稳定,导致急性冠脉综合征的发生,参与急性冠脉综合征的发生、发展过程,并在评估CHD发生的危险性中具有重要地位。

Objective. To investigate the changes and implication of C-reaction protein （CRP） in acute coronary syndrome. Methods： The level of CRP were tested by immunoturbidimetry in 73 patients with acute coronary syndrome（ACS）, and compared to that in 78 health people. Results： CRP level in patients with acute coronary syndrome（ACS） were significantly higher than that in health people（P〈0.01）. Conclusion： The concentration of CRP, higher in patients with acute coronary syndrome, results in instability of atheromatous plaque and ACS. The elevation of CRP plays a role in the development of ACS and is a key marker in evaluating the risk of ACS.