摘要
目的 探讨吉西他滨超液化碘油乳剂治疗晚期肝肿瘤的可行性及毒副反应。方法 46例肝晚期肿瘤，用吉西他滨超液化碘油乳剂栓塞治疗，部分直接灌注化疗，首次治疗后初步评估早期疗效及毒性反应。结果46例中，14例肺癌肝转移，10例胰腺癌肝转移，10例结肠癌肝转移，12例巨块型肝癌。首次治疗后，腹痛症状及食欲情况明显好转，而且其毒副作用不明显。结论 吉西他滨超液化碘油乳剂栓塞、灌注治疗肝肿瘤是安全的，而且能改善病人的生活质量，并且未见不可耐受副反应。
Objective To investigate the feasibility of Gemcitabine with Lipiodol Emulsion for treatment of advanced liver cancer and its sideeffects. Methods 31 advanced liver cancer cases were treated with Gemcitabine with Lipiodo Emulsion for arterial embolijation some were treated with arterial infusion chemotherapy. Early therapeutic effect and side effect were evaluated after the first initial therapy. Results In 31 patients, 4 patients were livermetastases from lung calcinoma, 8 patients were livermetastases from pancreatic carcinoma,7 patients were liver - maetastases from colorectal carcinoma, 12 patients were primary massive liver cancer After the first treament,the symptoms of gastrc pain and appetite were ameliorated , more over , the side - effects （ omit, hearttoxicity , myelosuppression） was slight. Conclusions Treament using gemcitabinte with lipiodol emulsion for arterial emboliyation and arterial infusion for chemthe - rapy in advanced liver cancer is not only safe but also improves the patients＇ quality of life the results suggested that the treamemt is mild in toxicity.
