摘要
目的探讨碱性磷酸酶(ALP)同工酶与肿瘤转移的相关性。方法用琼脂糖电泳法对50例体检健康者和134例恶性肿瘤患者血清中的ALP同工酶进行分析。结果肿瘤组的总ALP和同工酶活性均明显高于健康对照组;肿瘤组出现了胆汁型ALP,而健康对照组未出现,肿瘤组中有肝转移的胆汁型ALP活性高于其他各组;肿瘤组的骨型ALP活性高于健康对照组,而肿瘤组中有骨转移的骨型ALP活性高于其他各组。结论胆汁型ALP与肿瘤肝转移有一定的相关性,骨型ALP与肿瘤骨转移有一定的相关性。
Objective To discuss the relationship of alkaline phosphatase （ALP） isoenzyme and metastasis of carcinoma. Methods ALP isoenzyme in the serum of 50 normal healthy persons and 134 cases of tumors were analyzed by agarose electrophoresis. Results Total ALP and isoenzyme in the tumor group were higher than those in the normal group. Bile ALP was detected in the tumor group, but not in the normal group. Its activity in liver metastasis of carcinoma was higher than that in other groups prominently. Bone ALP in the tumor group was higher than that in the normal group. Its activity in bone metastasis of carcinoma was higher than that in other groups prominently. Conclusion There is relationship between bile ALP and liver metastasis of carcinoma, also between bone ALP and bone metastasis of carcinoma.
出处
《检验医学与临床》
CAS
2007年第7期577-578,共2页
Laboratory Medicine and Clinic
