老年人心肌缺血与心率变异性的相关性分析

Analysis of the relationship between the heart rate variability （HRV） and myocardial ischemia in elderly patients.

目的 研究老年人心肌缺血发作时心脏自主神经活动的特点.方法 对50例冠心病心肌缺血病人与40例正常人的心率变异性（HRV）各指标进行检测分析.结果 冠心病组SDNN、SDANN、RMSSD、PNN50、HF显著低于对照组（t=3.125～4.510,P＜0.01）,LF/HF显著高于对照组（t=3.268,P＜0.01）.心肌缺血发作时HF显著低于ST段压低后1h（t=3.375,P＜0.01）,而LF、LF/HF显著增高（t=3.210、3.925,P＜0.01）.结论 老年冠心病病人的自主神经活动受损,迷走神经张力减弱,而交感神经张力相对亢进,发生恶性心律失常的危险性增加.老年冠心病短暂性心肌缺血与HRV密切相关.

Objective To study the characteristics of heart autonomic nervous system in myocardial ischemia of elderly patients. Methods Study the HRV in group coronary artery disease （n = 50） and group control （n = 40）. Results Compared with group control , HRV （SDNN,SDANN,RMSSD,PNN50,HF） in group coronary heart disease was significantly decreased （t =3. 125 - 4.510,P 〈0.01） , LF/HF were significantly increased （t = 3. 268, P 〈 0.01 ）. With the attack of myocardial ischemia , HRV （HF） in group coronary heart disease was very significantly decreased （ t = 3. 375 , P 〈 0.01 ） , LF、LF/HF were very significantly increased （ t = 3. 210、3. 925, P 〈 0.01 ）. Conclusion Autonomic nervous system in senior citizen coronary artery disease is damaged , pneumogastric nerve is weakened and sympathetic nerve is sthenic, the fatalness of malignant arrhythmia increased, the transient myocardial ischemia in senior citizen coronary artery disease and HRV are nearly correlative.