1Gazdar AF,Bader S,Hung J,et al.Molecular genetic changes found in human lung caner and its precursor lesions[J].Coild Spring Harb Symp Quant Biol,1995,59:565-572.
2Sekido Y,Ahmadian M,Wistuba II,et al.Cloning of a breast cancer homozygous deletion junction narrows the region of search for a 3P21.3 tumor suppressor gene[J].Oncogene,1998,16(24):3 151-3 157.
3Dammann R,Li C,Yoon JH,et al.Epigenetic inactivation of a RAS association domain family protein from the lung tumor suppressor locus 3P21.3[J].Nat Genet,2000,25(3):315-319.
4Lerman MI,Minna JD.The 630 kb lung cancer homozygous deletion region on human chromosome 3P21.3[J].Cancer Res,2000,60(21):6 116-6 133.
5Ponting CP,Benjamin DR.A novel family of Ras-binding domains[J].Trends Biochem Sci,1996,21(11):422-425.
6Vos MD,Ellis CA,Bell A,et al.Ras use the novel tumor suppressor RASSF1 as an effector to medidate apoptosis[J].J Biol Chem,2000,275(46):35 669-35 672.
7Newton AC,Pvotein Kinase C.Seeing two domains[J].Curr Biol,1995,5(9):973-976.
9Hallberg B,Rayter SI,Downward J.Interaction of Ras and Raf in intact mammalian cells upon extracellular stimulation[J].J Biol Chem,1994,269(6):3 913-3 916.
10Burbee DG,Forgacs E,Zochbauer-Muller S,et al.Epigenetic inactivation of RASSF1 A in lung and breast cancers and malignant photype suppression[J].J Natl Cancer Inst,2001,93(9):691-699.
二级参考文献11
1Dammann R, Li C, Yoon JH, et al. Epigenetic inactivation of a ras association domain family protein from the lung tumour suppressor locus 3p21.3. Nat Genet, 2000,25:315-319.
2Wistuba I, Behrens C, Virmani AK, et al. High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints. Cancer Res, 2000,60: 1949-1960.
3Kok K, Naylor SL, Buys CH. Deletions of the short arm of chromosome 3 in solid tumors and the search for suppressor genes. Adv Cancer Res,1997, 71:27-92.
4Hung J, Kishimoto Y, Sugio K, et al. Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma.JAMA, 1995,273 : 558-563.
5Sekido Y, Ahmadian M, Wistuba II, et al. Cloning of a breast cancer homozygous deletion junction narrows the region of search for a 3p21.3 tumor suppressor gene. Oncogene, 1998,16:3151-3157.
6Lee MG, Kim HY, Byun DS, et al. Frequent epigenetic inactivation of RASSF1A in human bladder carcinoma. Cancer Res, 2001,61:6688-6692.
7Byun DS, Lee MG, Chae KS, et al. Frequent epigenetic inactivation of RASSFIA by aberrant promoter hypermethylation in human gastric adenocarcinoma. Cancer Res, 2001, 61: 7034-7038.
8Burbee DG, Forgacs E, Zochbauer-Muller S, et al. Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression. J Nat Cancer Inst, 2001,93 : 691-699.
9Vos MD, Ellis CA, Bell A, et al. Ras uses the novel tumor suppressor RASSF1 as an effector to mediate apoptosis. J Biol Chem, 2000,275:35669-35672.
10Palmisano WA, Divine KK, Saccomanno G, et al. Predicting lung cancer by detecting aberrant promoter methylation in sputum. Cancer Res, 2000,60:5954-5958.