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Ghrelin研究进展

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作者 张玉芳
出处 《医学理论与实践》 2007年第7期778-780,共3页 The Journal of Medical Theory and Practice
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参考文献30

  • 1Kojima M,Hosoda H,Date Y,et al.Ghrelin is a growth-hormone-releasing acylated peptide from stomach[J].Nature,1999,402:656-660.
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  • 3Cheng K,Chan WW,Butler B,et al.Evidence for a role of protein kinase-C in His-D-Trp-Ala-Trp-D-Phe-Lys-NH2-induced growth hormone release from rat primary pituitary cells[J].Endocrinology,1991,129:3337-3342.
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二级参考文献10

  • 1Kojima M, Hosoda H, Date Y, et al. Ghrelin is a growth-hormone-releasing acylated peptide from stomach[J]. Nature, 1999, 402:656-660.
  • 2Tschop M, Smiley DL, Heiman ML, et al. Ghrelin induces adiposity in rodents[J]. Nature, 2000, 407:908-913.
  • 3Tschop M, Wawarta R, Riepl RL, et al. Post-prandial decrease of circulating human ghrelin levels[J]. J Endocrinol Invest, 2001, 24:RC19-21.
  • 4Tschop M, Weyer C, Tataranni PA, et al. Circulating ghrelin levels are decreased in human obesity[J]. Diabetes, 2001, 50:707-709.
  • 5Man ZW, Zhu M, Noma Y, et al. Impaired (-cell function and deposition of fat droplets in the pancreas as a consequence of hypertriglyceridemia in OLETF rat, a model of spontaneous NIDDM[J]. Diabetes, 1997, 46:1718-1724.
  • 6Papotti M, Ghe C, Cassoni P, et al. Growth hormone secretagogue binding sites in peripheral human tissues[J]. J Clin Endocrinol Metab, 2000, 85:3803-3807.
  • 7Date Y, Murakami N, Kojima M, et al. Central effects of a novel acylated peptide, ghrelin, on growth hormone release in rats[J]. Biochem Biophys Res Commun, 2000, 275:477-480.
  • 8Wierup N, Svensson H, Mulder H, et al. The ghrelin cell: a novel developmentally regulated islet cell in the human pancreas[J]. Regul Pept, 2002, 107:63-69.
  • 9Date Y, Nakazato M, Hashiguchi S, et al. Ghrelin is present in pancreatic alpha-cells of humans and rats and stimulates insulin secretion[J]. Diabetes, 2002, 51:124-129.
  • 10Toshinai K, Mondal MS, Nakazato M , et al. Upregulation of Ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration[J]. Biochem Biophys Res Commun, 2001, 281:1220-1225.

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