女性生殖道人乳头瘤病毒感染相关因素分析

Study for relativity factor on reproductive tract with human papillomavirus on infection for women

目的:探讨女性生殖道人乳头瘤病毒(HPV)感染与常见妇科疾病的相互关系。方法:对950例有生殖道感染症状与体征的妇女,记录妇科检查所见,包括阴道充血、宫颈糜烂、宫颈息肉、宫颈肥大。采用聚合酶链反应技术测定HPV6、11和HPV16、18亚型。结果:单因素Logistic回归分析女性生殖道感染HPV与常见妇科疾病的相关性显示,宫颈糜烂与女性生殖道HPV6、11感染有明显的相关性(P=0.000),宫颈肥大与女性生殖道HPV16、18感染有明显相关性(P=0.002)。结论:对有妇科疾病症状与体征的妇女应进行HPV检测,并定期随访,尽早干预,从而减少各种生殖道感染及相关危险因素的发生率,提高妇女生殖健康水平。

Objective： To probe into the relationship for women with reproductive tract human papilloma viruses （HPV） infection and other disease. Methods： 950 women with reproductive tract infection symptom joined the program. Gynaeeology examinations included vagina hyperemia, cervical erosion, cervical polyp and cervical hypertrophy. The PCR technology was used to detect HPV6, 11, 16, 18. Results： The single factor Logistic recurrence analysis was used to analyze the relationship for women with reproductive tract HPV infection and other disease. The correlation of cervical erosion and reproductive tract HPV6, 11 infection was very high （ P = 0. 000 ） . The correlation of cervical hypertrophy and reproductive tract HPV16, 18 infection was very high （P = 0. 002） . Conclusion. It should be to detect HPV for women with abnormal reproductive tract symptom. Otherwise, they should be regularly followed up and intervened early, which will decrease all kinds of reproductive tract infection and improve women reproductive health level.