8[1]Slamon DJ, Godolphin W, Jones LA, et al. Studies of the HER/neu Proto-oncogene in Human Breast and Ovarian Cancer[J]. Science, 1989,2244:707 ～712.
9[2]Slamon DJ, Clark GM, Wong SG, et al. Human Breast Cancer: Correlation of Relapse and Survival with the Application of HER- Z/neu Oncogene[J ]. Science, 1987,235:177～182.
10[3]Shin C, Padhy LC, Murray M, et al. Transforming Genes of Carcinomas and Neurroblastomas Induced into Mouse Flbroblast[J ]. Nature, 1981,290:261 ～ 264.
6KAZKAYASI M, HUCUMENOGLU S, SIRINER G I, et al. Over-expression of p53 and c-erbB-2 oncoproteins in laryngeal carcinoma[J]. Eur Arch Otorhinolaryngol, 2001,258 : 329- 335.
7NADAL A, CARDESA A. Molecular biology of laryngeal squamous cell carcinoma[J]. Virchows Arch, 2003,442:1-7.
8BAZAN V, ZANNA I, MIGLIAVACCA M, et al. Prognostic significance of p16INK4a alterations and 9p21 loss of heterozygosity in locally advanced laryngeal squamous cell carcinoma [ J]. J Cell Physiol, 2002,1921 286-293.
9WALKER G J, HAYWARD N K. P16INK4A and P14ARF tumor suppressors in melanoma :lessons from the mouse[J]. Lancet, 2002,359 : 7- 8.
10SUH S I,PYUN H Y,CHO J W ,et al. 5-Aza-2'-deoxycytidine leads to down-regulation of aberrant p16INK4A RNA transcripts and restores the functional retinoblastoma protein pathway in hepatocellular carcinoma cell lines[J]. Cancer Lett,2000, 160 : 81 - 88.
