脑血管平滑肌钾通道与脑梗死的相关研究
摘要
脑血管平滑肌上主要存在有4类钾通道,它们在结构、功能和调控方面各有特点。对钾通道作用机制的深入研究将有助于发现治疗脑梗死新的有效手段。
出处
《神经疾病与精神卫生》
2007年第3期224-226,共3页
Journal of Neuroscience and Mental Health
参考文献18
-
1Horiuchi T,Dietrich HH,Tsugane S,et al.Role of potassium channels in regulation of brain arteriolar tone:comparison of cerebrum versus brain stem[J].Stroke,2001,32(1):218-224.
-
2Santa N,KitazonoT,AgoT,et al.ATP-sensitive potassium channels mediate dilatation of basilar artery in response to intracellular addification in vivo[J].Stroke,2003,34(5):1276-1280.
-
3Lohn M,Lauterbach B,Haller H,et al.beta(1)-Subunit of BK channels regulates arterial wall[Ca^2+ ] and diameter in mouse cerebral arteries[J].Appl Physiol,2001,91(3):1350-1354.
-
4A Cheong,A M Dedman,D J Beech.Expression and function of native potassium channel(Kvα1) subunits in terminal arterioles of rabbit[J].Physiol,2001,534(3):691-700.
-
5Horiuchi T,Dietrich HH,Dietrich HH,et al.Mechanism of extracellular K^+ -induced local and conducted responses in cerebral penetrating arterioles[J].Stroke,2000,33(11):2 692-2 699.
-
6Nguyen TS,Winn HR,Janigro D.ATP -sensitive potassium channels may participate in the coupling of neuronal activity and cerebrovascular tone[J].Am J Physiol Heart Circ Physiol,2000,278(3):H878-H885.
-
7Chrissobolis S,Sobey CG.Influence of gender on K+ -induced cerebral vasodilatation[J].Stroke,2004,35 (3):747-752.
-
8Nakahata K,Kinoshita H,Tokinaga Y,et al.Vasodilation mediated by inward rectifier K^+ channels in cerebral microvessels of hypertensive and normotensive rats[J].Anesth Analg,2006,102 (2):571-576.
-
9Erdos B,Simandle SA,Snipes JA,et al.Potassium channel dysfunction in cerebral arteries of insulin-resistant rats is mediated by reactive oxygen species[J].Stroke,2004,35 (4):964-969.
-
10Gerzanich V,Zhang F,West GA,et al.Chronic nicotine alters NO signaling of Ca(2 +) channels in cerebral arterioles[J].Circ Rea,2001,88(3):359-365.
-
1林金嬉.皮层下动脉硬化性脑病的临床及脑血管病理特点[J].中国卒中杂志,2007,2(6):491-496. 被引量:10
-
2王政伟,尹彦玲,周岱,鲍耀东.氧合血红蛋白诱导脑血管平滑肌细胞凋亡的研究[J].中风与神经疾病杂志,2002,19(3):187-187. 被引量:1
-
3成志.葛根素治疗脑梗塞的疗效观察[J].衡阳医学院学报,1998,26(1):101-102. 被引量:3
-
4郑秉杰,赵世光.脑血管平滑肌钾通道与脑血管痉挛[J].国际脑血管病杂志,2009,17(8):623-625.
-
5李社会,张晶,牛福来,王建祯.尼莫通与调心方联合应用改善帕金森病认知功能障碍80例临床分析[J].中国老年学杂志,2003,23(9):616-616. 被引量:1
-
6李雪石.蛛网膜下腔出血后脑血管痉挛的发生机制研究[J].医学综述,2009,15(7):1065-1066.
-
7赵光丽,孙忠国,梁咏梅.培他啶与复方丹参联合治疗眩晕[J].华北煤炭医学院学报,2002,4(2):227-228.
-
8杨森.全麻患者吸入七氟醚时脑动脉血流的变化[J].中国医药指南,2012,10(15):180-181.
-
9程智刚,谭秀娟.一氧化氮与脑缺血缺氧损伤研究进展[J].国外医学(麻醉学与复苏分册),1995,16(6):352-355. 被引量:5
-
10李龙珠,刘家军,李贤玉,吴胜英,郭俐宏.丹红注射液对大鼠局灶性脑缺血再灌注损伤血管内皮生长因子表达的影响[J].实用药物与临床,2015,18(8):897-900. 被引量:13