酷似干燥综合征起病的多中心型Castleman病1例报告并文献复习

Multicentric Castleman's Disease with Initial Symptoms Similar to Sjogren's Syndrome:One Case Report and Literature Review

目的:探讨Castleman病的起病和临床特点。方法:对1例酷似干燥综合征起病的Castleman病患者的临床资料进行分析,并复习文献。结果:本例临床先以酷似干燥综合征为首发症状,随后出现淋巴结肿大,经多次淋巴结活检,最后确诊为多中心型Castleman病。结论:Castleman病可继发于自身免疫性疾病,临床表现多种多样。对不明原因伴淋巴结肿大的患者应反复多次淋巴结活检才能作出正确诊断。

Objective：To investigate the clinical features of Castleman＇s disease（CD）. Methods：To report one case of Castleman＇s disease with the initial symptoms similar to Sjogren＇s syndrome and review the related literatures. Re-sults..A 65-years-old man with the initial symptoms similar to Sjogren＇s syndrome was admitted to hospital, then diagnosed as multicentric Castleman＇s disease after lymph node biopsy was performed for over three times. Conclusion：CD may be secondary to autoimmune diseases and its clinical features are variable. Lymph node biopsy should be performed several times in the patients with unexplained lymphad enectasis.