炎症和动脉血栓形成

Inflammation and Arterothrombosis

动脉粥样硬化已不再被考虑是由于脂质代谢异常的疾病,事实上动脉粥样硬化可能是在临床出现征状之前已存在数十年的炎症过程,一旦启动特殊的细胞因子介导的事件在动脉壁中进行,炎症的生物标志物如C反应蛋白是有用的。

atherosclerosis is no longer considered a disorder due to abnormalities in lipid metabolism. In fact,the inciting event of atherosclerosis is likely an inflammatory insult that occurs decades before the disease becomes clinically apparent. Once initiated, specific cytokine-mediated events in the arterial wall are progresses. The clinical application of inflammatory biomarker such as C-reactive protein is useful.