生殖道支原体与女性不孕不育和抗子宫内膜抗体的关系

Study of association among mycoplasma infection,AEMAb and female infertility

目的研究女性不孕不育和生殖道解脲支原体(U.urealyticum,UU)、人型支原体(M.hom in is,MH)和抗子宫内膜抗体(Antiendom etrium antibody,AEMAb)的关系。方法采用培养法分别对108例原发性和96例继发性不孕不育患者宫颈分泌物进行UU,MH检测;采用ELISA检测血清中AEMAb。结果原发性和继发性不孕不育组UU,MH感染率及AEMAb阳性率与对照组比较差异均有显著性(P<0.00167=。不孕组中支原体感染阳性患者AEMAb阳性率明显高于支原体阴性患者(P<0.05)。结论女性不孕不育与生殖道支原体感染和AEMAb的产生有密切关系,为临床诊断和合理治疗不孕不育患者提供了理论依据。

Objective： To investigate the association of ureaplasma urealyticum （UU） and mycoplasma hominis （MH） infection with antiendometrium antibody （AEMAb） in infertile women. Methods： UU and MH were detected respectively in the cervical secretion of 108 primary infertile women and 96 secondary infertile patients. The AEMAb in all infertile patients sero was measured by ELISA. Results： The infection rates of UU and MH both in primary infertile group and in secondary infertile group were significantly higher than those in the control. The positive rate of AEMAb was also higher remarkably than that in the control group （ P 〈0. 00167 =. The positive rate of AEMAb in the group of infertile patients infected with UU and MH was higher significantly than that in negative patients （ P 〈 0.05 ）. Conclusion： There was closely correlation between mycoplasma infection in female urogenital tract and AEMAb in female infertility. Our results may provide an theoretical evidence for the clinical diagnosis and reasonable treatment of female infertility.