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抑制素在多囊卵巢综合征中的研究进展 被引量：2

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摘要 抑制素(Inhibin,INH)是一种糖蛋白激素,近10年来,随着它在女性生殖生理及病理中的深入研究,发现INH是监测卵泡募集和优势卵泡选择以及卵泡活性的有价值指标,并与多囊卵巢综合征(Polycystic ovary syndrome,PCOS)的发病机理有着重要的内在联系,参与了PCOS的发生与发展。本文就INH在PCOS发病机制中的进展作一综述。
作者 胡毅娜 靳镭
机构地区 华中科技大学同济医学院附属同济医院妇产科生殖中心
出处 《中国优生与遗传杂志》 2007年第7期117-119,共3页 Chinese Journal of Birth Health & Heredity
关键词 抑制素 多囊卵巢综合征 体重指数 卵巢储备
分类号 R711.75 [医药卫生—妇产科学]
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参考文献21

  • 1Philip K,Kalyana CN,Analia T,et al.Significance of inhibin in reproductive pathophysiology and current clinical applications.Reproductive BioMedicine online[J].2005,10(6):786-796.
  • 2Luisi s,Florio p,Rcis FM,et al.Inhibins in female and male reproductive physiology:role in gametogenesis,conception,implantation and early pregnancy[J].Hum Reprod Update,2005,11,123-135.
  • 3Fanchin R,Cunha Filho JS,Schonauer LM,et al.Luteal estradiol administration strengthens the relationship between day 3 follicle-stimulating hormone and inhibin B levels and ovarian follicular status.[J].Fertil Steril,2003,79(3):585-589.
  • 4Roger Hart,Martha Hickey,Stephen Franks.Dwfinitions,Prevalence and symptoms of polycystic ovaries and polycystic ovary syndrome[J].Clinical Obstetrics and Gynaecology,2004,18(5):671-683.
  • 5Tinkanen H,Blauer M,Laippala P,et al.Correlation between serum inhibin B and other indicators of the ovarian function[J].Eur Obstet Gynecol Reprod Biol,2001,94(1):109-113.
  • 6Xuesong wen,Amanda J Tozer,Stephen A.Follicular fluid levels of inhibin A,inhibin B,and activin A levels reflect changes in follicle size but are not independent markers of the oocyte's ability to fertilize[J].Fertil Steril,2006,85(6):1723-1729.
  • 7Mariet W Elting,Ph.D Aging women with polycystic ovary syndrome who achieve regular menstrual cycles have a smaller follicle cohort than those who continue to have irregular cycles[J].Fertil Steril,2003,79(5)1154-1160.
  • 8Wills DS,Watson H,Mason HD,et al.Premature response to luteinizing hormone of granulosa cells from anovulatory.women with polycystic ovary syndrome:relevance to mechanism of anovulation[J].Clin Endocrinol Metab,1998,83(11):3984.
  • 9Welt CK,Schneyer AL.Differential regulation of inhibin B and inhibin A by follicle-stimulating hormone and local growth factors in humangranulosa cells from small antral follicles[J] Clin Endocrinol Metab,2001,86:330-336.
  • 10Welt CK,Smith ZA,Pauler DK,et al.Differential regulation of inhibin A and inhibin B by luteinizing hormone,follicle stimulating hormone,and stage of follicle development[J].Clin Endocrinol Metab,2001,86:2531-2537.

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中国优生与遗传杂志
2007年 第7期

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