对氧磷酶1与子痫前期关系的研究进展
摘要
对氧磷酶(paraoxonase,PON)是一类钙依赖性的芳香酯酶,在脂类代谢中具有重要的抗氧化活性可在对抗氧化应激导致的内皮功能受损方面发挥重要作用。当其活性下降时降低的抗氧化水平和升高的脂质过氧化产物可能导致对血管内皮的损坏并引起子痫前期临床症状的出现。
出处
《中国优生与遗传杂志》
2007年第7期120-121,共2页
Chinese Journal of Birth Health & Heredity
参考文献16
-
1Redman CW,Sargent IL.The pathogenesis of pre-eclampsia[J].Gynecol Obstet Fertil,2001,29:518-522.
-
2Harel M,Aharoni A,Gaidukov L,et al.Structure and evolution of the serum paraoxonase family of detoxifying and antiatherosclerotic enzymes[J].Nat Struct Mol Biol,2004,11(5):412-419.
-
3Ecobichon DJ,Stephens DS.Perinatal development of human blood esterases[J].Clin Pharmacol Ther,1973,14:41-47.
-
4Ferre N,Camps J,Fernandez-Ballart J,et al.Longitudinal changes in serum paraoxonase-1 activity throughout normal pregnancy[J].Clin Chem Lab Med,2006,44(7):880-2.
-
5Mackness MI,Mackness B,Durrington PN.Paraoxonase and coronary heart disease[J].Atheroscler Suppl,2002,3(4):49-55.
-
6Rozenberg.Paraoxonase (PON1) deficiency is associated with increased macrophage oxidative stress:studies in PON1-knockout mice[J].Free Radic Biol Med,2003,34(6):774-784.
-
7Young Ju Kim,Hyesook Park,Hwa Young Lee,et al.Paraoxonase gene polymorphism,serum lipid,and oxidized low-density lipoprotein in preeclampsia[J].Eur J Obstet Gynecol Reprod Biol(2006).doi:10.1016/j.ejogrb.2006.07.046.
-
8Jarvik GP,Rozek LS,Brophy VH,et al.Paraoxonase (PON1) phenotype is a better predictor of vascular disease than is PON1192 or PON155 genotype[J].Arterioscler Thromb Vasc Biol,2000,20:2441-2447.
-
9Ferrè N,Camps J,Prats E,et al.Serum paraoxonase activity:a new additional test for improved evaluation of chronic liver damage[J].Clin Chem,2002,48(2):261-268.
-
10Nguyen SD,Sok DE.Oxidative inactivation of paraoxonase1,an antioxidant protein and its effect on antioxidant action[J].Free Radic Res,2003,37(12):1319-30.
-
1石溪,周晓梅.对氧磷酶1与多囊卵巢综合征的相关性研究[J].医学综述,2011,17(19):2983-2985.
-
2李玉琴,罗美瑜.对氧磷酶与妊高征关系的研究[J].海峡预防医学杂志,2005,11(4):27-29.
-
3张玉瑾,刘宏伟,白怀,范平.对氧磷酶-1与多囊卵巢综合征关系的研究进展[J].中华妇幼临床医学杂志（电子版）,2015,11(2):105-109.
-
4唐三华,匡希斌.对氧磷酶生物学特性与心血管疾病研究进展[J].社区医学杂志,2012,10(3):14-16. 被引量：4
-
5曾宪钦,胡雪松.血清PON1活性与冠状动脉粥样硬化研究新进展[J].中国实用医药,2008,3(12):179-181. 被引量：4
-
6李玉琴,罗美瑜,张廷彰.子痫前期患者血清对氧磷酶活力检测及其意义[J].海峡预防医学杂志,2011,17(3):82-84.
-
7李淑玉.腹腔镜下保守手术与腹腔镜下输卵管切除术治疗输卵管妊娠的对照研究[J].中外医疗,2016,35(20):13-15. 被引量：4
-
8岳文芳,李季滨,李丽,范爱华,王丽琴.子痫前期患者血清对氧磷酶活性及脂质过氧化与血脂变化的相关性研究[J].中国全科医学,2011,14(8):851-853. 被引量：1
-
9许宏伟,赵真,肖波,杨晓苏,杨期东,唐北沙.对氧磷酶2基因G/A148多态性与脑出血的关系[J].中华内科杂志,2006,45(12):1027-1027.
-
10熊俊,唐卉,王素梅.脂代谢影响因素与妊娠期高血压疾病相关性研究进展[J].实用妇产科杂志,2014,30(4):256-259. 被引量：21
