不同采集模式门控心肌显像对左室功能参数测定的影响

Effect of gated myocardial perfusion imaging with different acquisition models on the determination of left ventricular function

目的比较16帧和8帧采集模式下99Tcm-MIBI门控心肌显像对测定左室舒张末期容量(EDV)、收缩末期容量(ESV)、左室射血分数(LVEF)的影响。方法91例患者,在相同条件下分别进行每个心动周期为16帧和8帧的门控采集。采用GSQuant软件分别计算出两种采集方法的EDV、ESV、LVEF,并进行比较。结果(1)16帧和8帧门控采集对左室功能测定的重复性好,变异系数(CV)均小于2%。(2)16帧和8帧门控采集测定的EDV、ESV和LVEF分别为(68.2±20.5)ml、(20.9±11.9)ml和(71.3±9.2)%,(74.9±21.9)ml、(26.2±13.9)ml和(66.9±9.5)%。16帧测定的EDV、ESV值较8帧测定的小(P<0.01),但其测定的LVEF值较8帧高(P<0.01)。结论16帧和8帧采集的门控心肌显像测定的EDV、ESV和LVEF值有很好的相关性。

Objective To compare 16-frame with 8-frame ^99Tc^m-MIBI gated myocardial perfusion imaging （G-MPI） for determination of end-systolic volume （ESV）, end-diastolic volume （EDV） and left ventricular ejection fraction（LVEF）. Methods Ninety-one patients underwent G-MPI imaging using 16-frame per cardiac cycle acquisition, and then were examined using 8-frame in the same condition immediately. Left ventricular volumes and LVEF were measured by GS Quant Software about 16-frame and 8-frame images. The correlation of left ventricular volumes and LVEF with these two methods were compared. Results The reproducibility of GS Quant measuring left ventricular function and LVEF was perfect （CV 〈 2 %） . The values of EDV, ESV and LVEF measured by 16-frame and 8-frame G-MPI were 68. 2 ± 20.5 ml, 20.9 ± 11.9 ml and 71.3 ± 9.2%, 74. 9±22.9 ml,26. 2±23.9 ml and 66.9±9.5%, respectively. The correlation was also fine between the values measured by 16-Frame and 8-frame （P 〈 0.01 ）. 16-frame acquisition resulted in significantly smaller EDV （P〈0. 01）, smaller ESV （P〈0. 01） and higher LVEF （P〈0.01） than 8-frame G-MPI. Conclusion There is a perfect correlation in LVEF between the two methods.