肾上腺嗜酸细胞腺瘤一例报告并文献复习

Adrenocortical oncocytoma： one case report and review of literature

目的报道1例肾上腺嗜酸细胞腺瘤患者的临床及病理特点。方法患者,男,37岁,体检发现左肾上腺肿物15 d入院。既往否认高血压、低血钾等病史。实验室检查血钾、血儿茶酚胺、血皮质醇、立卧位肾素血管紧张素、醛固酮、尿3-甲基-4-羟基苦杏仁酸、尿17-羟皮质类固醇、17-酮皮质类固醇均正常。B超及CT检查示左肾上腺区肿物,直径约7 cm。术前诊断为左肾上腺区肿物,行后腹腔镜下左肾上腺肿物切除术。结果术中发现肿物体积较大,包膜完整光滑,与周围组织无粘连,肿物表面血管较为丰富,术中碰触肿物,血压无波动,完整切除肿物。术后病理检查示肿瘤细胞嗜酸性,内部充满颗粒,诊断为肾上腺嗜酸细胞腺瘤。随访2个月无复发。结论肾上腺嗜酸细胞腺瘤是一种具有潜在恶性的良性肿瘤,可手术切除,但需密切随访。

Objective To report the clinical features and pathologic findings of an adrenocorticat oncocytoma. Methods The patient, male, 37 years old, was found left adrenal mass by B-ultrasonography, with no special medical history. CT showed a 7 cm adrenal mass and the serum renin, aldosterone, catechoamine level were nomal. Then laparoscopic adrenalectomy was performed. Resuits The mass was eompletely encapsulated. The microscopic histology showed the tumor cells were polygonal, with abundant granular, eosinophilic cytoplasm. The pathological diagnosis was adrenocortical oncocytoma. There was no recurrence been found after 2 months follow-up. Conclusions Adrenocortical oncocytoma is a rare benign neoplasm. An adrenatectomyis preferred as treatment.