摘要
Atherosclerosis is a multiple-pathogeny disease that consists of many complicated processes,including oxidative stress,endothelium dysfunction,abnormal cell proliferation,apoptosis and extracellular matrix disorder.The pivotal proteases for these courses are NAD(P)H oxidase,eNOS,MAPKs and MMPs,respectively.As an upstream kinase,protein kinase C(PKC) may involve in the development of atherosclerosis through affecting these enzymes.
Atherosclerosis is a multiple -pathogeny disease that consists of many complicated processes, including oxidative stress, endothelium dysfunction, abnormal cell proliferation, apoptosis and extracellular matrix disorder. The pivotal proteases for these courses are NAD（P） H oxidase, eNOS, MAPKs and MMPs, respectively. As an upstream kinase, protein kinase C （PKC） may involve in the development of atherosclerosis through affecting these enzymes.
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
2007年第7期1442-1445,共4页
Chinese Journal of Pathophysiology
基金
湖南省医药卫生科研计划资助项目(NoB2004-082)
湖南省自然科学基金资助项目(No05JJ40039)
