839例宫颈TCT细胞学检测结果及临床分析

The Clinical Analysis of the Results of Thinprep Liquied Based Cytology Test in 839 cases of Cervical Lesions

目的:应用Thinprep液基薄层细胞学技术(TCT)及TBS诊断系统,探讨宫颈癌及癌前病变的相关因素及临床细胞学特点。方法:对839例受检者的宫颈脱落细胞采用TCT检测和TBS分类诊断,将ASCUS以上病变列为细胞学阳性病例,分析不同宫颈病变及其与临床的关系。结果:839例受检者TCT标本满意率为96.36%,细胞学阳性病例103例,总检出率12.28%,其中ASC-US+AGUS占6.32%;LSIL占2.74%;HSIL占3.10%;CA占0.12%;HPV感染87例(10.37%)。在103例TCT阳性病例中:宫颈光滑-轻糜组与中-重糜组分别占51.74%和48.26%;正常或轻度炎组占40.05%,中度炎组占27.53%,重度炎组占32.42%。结论:TCT和TBS系统能准确反映宫颈病变情况,HPV是宫颈CIN的重要相关因素,预防HPV感染、筛查和监测HPV感染对象、治疗及阻止CIN病变升级是防止宫颈癌的关键。

Objective：To investigate the relative factors and clinicocytologic features of cervical carcinoma and precancerous lesions by TCT and The Bestbesda system （TBS）. Methods：839 cases were detected by TCT and TBS, then the clinical relatives of the different cervical lesions were anslyzed. Results：The satisfactory rate of TCT samples was 96.36%. The 839 cases, the positive rate of TCT cytology was 12.28 % ; 87 cases （ 10.37% ） HPV infection. Of 103 positive cases, 53 cases were diagnosed ASCUS and AGUS （6.32%）, LISL（2.74% ）, HSIL（3.10% ）, CA（0.12% ） ; the rate of smooth - slight erosion group is 51.74% and the mid - serve erosion is 48.26% ; the normal or slight inflammation is 40.05%, the serve inflammation is 32.42%, the moderate inflammation is 27.53%. Conclusions ：TCT and TBS can accurately reflected the cervical lesions, the extent of cervical erosion is not correlated with the positive rate of cervical lesions, the incidence of HPV infection is the important correlative factor of CIN. In order not to be infected by HPV, efficient screening and surveying of HPV infection, curing and blocking the evolving of CIN are the key points to prevent cervical carcinoma.