64层螺旋CT冠状动脉成像在冠心病早期诊断的价值

Value of 64-slice computed tomographic angiography for early diagnosis of coronary artery disease

目的探讨64层螺旋计算机断层扫描冠状动脉成像(64-slice computed tomographic coronary angiography,CTA)早期诊断冠心病的临床价值。方法回顾性分析行CTA和冠状动脉造影的临床疑诊冠心病病人65例,以冠状动脉造影结果为标准,评估CTA诊断冠状动脉中重度狭窄(≥50%)的准确性。结果CTA诊断冠状动脉中、重度狭窄的敏感性、特异性、阴性预测值、阳性预测值和准确度分别为92.7%、91.7%、81.9%、96.9%和92.0%。结论CTA诊断冠状动脉中、重度狭窄具有较高的准确性,适合用于临床怀疑冠心病的的筛选检查。

Objectives To evaluate the clinical values of 64-slice computed tomographic coronary angiography （CTA） for early diagnosis of coronary artery disease by compared with coronary angiography （CAG）. Methods During Sep. 2006 to Feb. 2007, we retrospectively analyzed data of 65 patients who were suspected to have coronary artery disease undergoing 64-slice CTA and CAG within a time frame of one week in our hospital, in order to evaluate the accuracy of 64-slice CTA in detecting mild to severe stenosis of the coronary arteries by taking CAG as the references. Results The diagnostic sensitivity, specificity, positive predictive value, negative predictive value and accuracy of 64-slice CTA to detect more than 50% diameter stenosis lesion were 92.7%, 91.7%, 81.9%, 96.9% and 92.0%, respectively. Conclnsions Sixty fourslice CTA has high accuracy in detecting mild to severe stenosis of the coronary arteries, therefore, it is efficient in screening coronary artery disease.