儿童交替性偏瘫的诊断与治疗

Diagnosis and treatment for alternating hemiplegia in children

为探讨儿童交替性偏瘫的临床特点及治疗方法，对近１３年收治的８例患儿的临床资料进行分析。结果表明，其临床特征为１８个月前起病，有频繁发作的交替性偏瘫，常伴锥体外系症状及认知功能减退，睡眠可缓解上述症状。应用尼莫地平或氟桂嗪治疗后，发作频率明显降低，发作持续时间明显缩短。提示钙离子拮抗剂对本病治疗有效。

To study the clinical characteristics and treatment for alternating hemiplegia of childhood (AHC), we analysed clinical data of 8 children with AHC. They were characterized by the onset before 18 months of age and by frequent episodes of alternating paralysis with extrapyramidal symptoms and congnitive impairment. Sleep could relieve the above symptoms. A reduction in frequency and shortening of duration of hemiplegia attacks were observed after the treatment with flunarizine or nimodipine. The results suggest that calcium antagonist be effective in treating AHC.