骨科住院患者下肢深静脉血栓形成的危险因素及相关性分析

Correlative Analysis of Risk Factors of Deep Vein Thrombosis in Lower Extremity in Orthopedic Inpatients

目的探讨骨科住院患者下肢深静脉血栓形成（lower extremity deep vein thrombosis，LD-VT）的危险因素。方法2003年8月-2006年8月收治的350例骨科住院患者中，确诊为LDVT者38例，对其相关因素进行回顾性分析。结果27项单因素相关分析中有9项有显著性意义，经Logis-tic回归分析显示，危险因素为：血浆D-二聚体、纤维蛋白原、血管性血友病因子阳性，4周内有手术史以及有外伤史。结论对上述危险因素存在的骨科住院患者，应警惕LDVT发生，如有D-二聚体测定阳性等危险因素应予预防性治疗。

Objective To study the risk factors of deep vein thrombosis in lower extremity （LDVT） in orthopedic inpatients. Method Retrospective study was adopted in 350 orthopedic inpatients from August 2005 to August 2006. 38 patients were selected as study objects whom final diagnosed LDVT by Doppler ultrasonic flowmeter and phlebography, others of non-LDVT as control group. Results In all of the 27 factors, there were 9 single correlative factors showed significance （ P 〈0. 05 ）. And 5 items showed significance while Logistic regression analysis was performed further, which were D-dimer （ ＋ ）, FG（ ＋ ）, vWF（ ＋ ）, operation history in 4 weeks and trauma history. Conclusion Prophylactic treatment may be used for the orthopedic inpatients when the risk factors were tested positive.