粘细菌次级代谢产物及其在农业上的应用价值

Myxobacterial Secondary Metabolites and Their Potential Applications in Agriculture

粘细菌具有独特的形态发生行为和产生活性次级代谢物的杰出能力,其许多次级代谢产物主要表现较强的抗真菌活性,而且作用机制新颖多样。粘细菌及其抗性代谢产物具有开发成抗真菌制剂作为农用化学品应用的潜力。主要综述了粘细菌次级代谢产物的结构特点、活性作用机制以及具有农用抗生素开发潜力的主要代谢产物。

Myxobacteria are fascinating and unique bacteria with uncommon morphogenetic behavior and extraordinary capacity to produce biological secondary metabolites with various mechanisms. The action spectrum of myxobacterial secondary metabolites are mainly in eukaryotic cells, normally with novel mechanisms. Myxobacteria and their natural products are in great potentiality to be developed as new antifungal agents for agrochemical uses. In this paper, we summarized myxobacterial secondary metabolites of their structural characteristics and action mechanisms. Some antifungal metabolites and their potential agricultural applications are discussed in details.