单纯胶原酶与联合切吸治疗脱垂型腰椎间盘突出症疗效分析

The clinical analysis of collagenase chemonucleolysis or combining with automated perculaneous lumbar discectomy in treating patients with lumbar intervertebral disc prolapsus

目的：分析单纯胶原酶与联合切吸治疗脱垂型腰椎间盘突出症临床疗效。方法：对71例脱垂型腰椎间盘突出症患者，根据椎间盘突出的髓核向下滑移的程度分为两组：脱垂（A组）与重度脱垂组（B组）。A组30例，B组41例。A组采用APLD＋胶原酶溶解术，B组采用单纯胶原酶溶解术，通过6—33个月的随访对其疗效进行分析。结果：两组患者治疗后3个月、6个月、12个月的优良率分别是76．7％、83．3％、86．7％和74．6％、82．2％、85．4％。结论：单纯胶原酶与联合切吸治疗脱垂型腰椎间盘突出症疗效明显，可使一些严重脱垂的腰椎间盘突出症患者免除手术治疗。

Objective To analyse the clinical effectiveness with CCNL or combining with APLD in treating patients with lumbar disc prolapsus. Methods 〉1 patients with lumbar intervertebral disc prolapsus were analysed. According to the degree of shifting group A which the shifting of vertebral pulp, we divided these cases into two groups, there were 30 cases in of vertebral pulp is severe, and 41cases in group B which was slight. CCNL combining with APLD was applied to group A and CCNL to group B. Results Following up through 3 months 6 months and 12 monthsr, the ratios of excellent or good was 76.7%,83.3%,86.7% and 74.6%,82.2%,85.4% in group A and group B respectively. Conclusion CCNL or combining with APLD is a good method in treating lumbar disc prolapsus with high effectiveness, and can make some patients with severe prolapsus exempting from surgery.