重症支原体肺炎35例治疗分析

The clinical investigation of severe mycoplasmai pneumonia diagnosis and therapy

目的 探讨重症支原体肺炎的有效诊治方法。方法 重症支原体肺炎35例随机对照分组：采用单纯治疗方案即单用大环内酯类抗生素（阿奇霉素）治疗16例，采用联合治疗方案即用阿奇霉素联合激素和丙种球蛋白等治疗19例，评价不同治疗方案疗效差别。结果重症支原体肺炎的单纯治疗方案有效率为43．8％，联合治疗方案有效率为78．9％，差异有统计学意义（四格表X^2检验、X^2=4．609、P=0．03）。结论 重症支原体肺炎须用大环内酯类抗生素联合激素和丙种球蛋白治疗方能取得良好的疗效。

Objective To evaluate the approach of severe mycoplasmal pneumonia diagnosis and therapy and evaluate the effect difference of different therapy proposal to severe mycoplasmal pneumonia. Methods The retrospective research was done in the Second Affiliated Hospital of Guangzhou Medical College from May 8,2004 to October 30,2006. Thirty five cases of severe nlycoplasmal pneumonia were diagnosed. Single approach macrolides and combinarive treatment macrolides combined with corticosteroids or gamma globulin approach were given and evaluated the effect of the treatment to severe mycoplasmal pneumonia. Results To treat with single proposal the effect ratio was 43.8 %. To treat with combinative therapy proposal,the effective ratio was 78.9 % . The therapy effect difference was statistically significant. Conclusion For severe mycoplasmal pneumonia,the combination of macrolides antibiotic and steroid and gamma globulin therapy proposal must be given and the therapeutic efficacy will be achieved.