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基质细胞衍生因子-1与增生性糖尿病视网膜病变的研究进展 被引量:5

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摘要 基质细胞衍生因子(SDF)-1是骨髓基质细胞产生的CXC类趋化因子蛋白,其广泛表达于多种细胞(免疫细胞)和器官组织(包括心、脑、肝、脾、肺和肾)中,在免疫、循环及中枢神经系统的发育中起着重要作用。本文从SDF-1与CXC趋化因子受体(CXCR)4的结构、作用和调节,SDF-1与眼新生血管,以及其与增生性糖尿病视网膜病变(PDR)和SDF-1抗体治疗PDR进行综述。
出处 《世界临床药物》 CAS 2007年第7期394-397,403,共5页 World Clinical Drug
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