BTCA交联丝素机制的研究

Study on the mechanism of crosslinking between BTCA and silk fibroin

选用丙氨酸、丝氨酸和桑蚕丝丝素为研究对象，采用热重分析（TG）对BTCA交联丝素的机制进行研究，研究比较了BTCA和丙氨酸、丝氨酸、桑蚕丝丝素系统在100-200℃范围内的TG曲线。结果表明：在次磷酸钠的催化作用下，BTCA和丝氨酸、丝素都可以产生化学反应，而和丙氨酸没有化学反应。由于丝氨酸在化学结构上有羟基存在，而丙氨酸在化学结构上没有羟基存在，因而在普通免烫整理条件下，BTCA交联丝素的主要形式仍然是和羟基反应产生的酯交联。

Alanine, serine and silk were used as model chemicals and material to study the mechanism of crosslinking between BTCA and silk fibroin via TG analysis. The study compared the TG curves of BTCA and alanine, serine , silk between 100 - 200 ℃ ,The data showed that except alanine, BTCA exhibited big weight loss when mixed with serine and silk under normal durable press finishing conditions in the presence of NaHPO2. For the serine has hydroxyl in the structure while alanine has not, so the data indicate definitely that the main crosslinking during the durable press finishing of silk using BTCA is still the ester link.