大肠癌患者术后血清CEA含量的检测及临床意义

The serum level of CEA and clinical singificance in postoperative patients with colorectal carcinoma

为探讨大肠癌患者术后血清CEA含量对预后的判定、监测肿瘤有无复发和转移的价值，我们对204例大肠癌术后患者的血清CEA含量进行了动态观察。30例只做姑息切除的患者，术后22例CEA检测阳性，肿瘤完整切除的174例病人中，仅6例CEA阳性。随访中72例出现肿瘤复发或转移的病人中，58例CEA阳性，而无复发的大肠癌病人，CEA值全部阴性。结果表明:术后6周检测血清CEA含量，可了解肿瘤是否残留，术后动态观察血清CEA的含量，如降为正常的CEA值再度升高，则提示肿瘤复发或转移。

Carcinoembryonic antigen (CEA)is frequently used in the diagnosis of the Colorectal Carcinoma. In this study, postoperative level of serum CEA was measured in 2o4 cases of colorectal carcinoma. In patients with palliative operation,relapse and metastasis the positive rate was markedly elevated (P＜0.01),especial ly in patients with liver metastasis. The results indicate that use of CEA is an useful adjunct diagnostic measure for postoperative patients with coloractal carcinoma,and is helpful in the assessment of the stage of the disease,in the diagnosis of the relapse as well as the metastasis