浙江省8～10岁儿童甲状腺容积正常值及校正方法的研究

Study on the upper limit and its revision method of normal thyroid volume of children of 8-10 years-old in Zhejiang Province

目的探讨全民加碘10年后浙江省8-10岁儿童的甲状腺容积的正常值及其校正方法,建立浙江省8-10岁儿童甲状腺容积的正常值标准。方法以2005年全国第5次碘缺乏病监测中的浙江省1110名8-10岁儿童B超测得的甲状腺容积数据为基础,应用SPSS10.0 for windows统计软件进行统计分析检验。结果儿童甲状腺容积随着年龄的增加而递增,性别对甲状腺容积没有影响。浙江省8-10岁儿童甲状腺容积的正常值标准按年龄分组分别为：4.7、5.3和6.0ml。体质指数校正法（BMIV）、体重身高甲状腺容积指数法（WHVI）、体表面积甲状腺容积指数法（BSAV）和身高甲状腺容积指数法（HVI）四种甲状腺容积校正方法中,HVI校正法比其它校正方法更方便实用。结论浙江省8-10岁儿童甲状腺容积各年龄段的正常值标准较为合理,可为今后浙江省碘缺乏病监测及我国修订儿童甲状腺容积正常值标准提供依据。HVI是目前校正甲状腺容积的最适合方法。

Objective To study the upper limit of normal thyroid volume based children 8 - 10 years old in Zhejiang Province. At the same time, the revision methods of thyroid volume were discussed. Methods The thyroid volume of 1110 children 8- 10 years old in Zhejiang province, was measured by uhrasonography during the fifth national survey of IDD in 2002 and was analyzed by using SPSS 10.0 for Windows. Results 1. Children＇s thyroid volume was progressively increased with age. But there was no significant difference between boys and girls. 2. The upper limit of normal thyroid volume of children at the age of 8, 9 and 10 years old in a province were 4.7, 5.3 and 6.0ml respectively. The upper limit of normal thyroid volume in children at the age of 8 and 9 is higher than the corresponding oriteria of GB16398 - 1996. 3. Of all the four revision methods of thyroid volume, HVI was better than others. ConcIusions 1. The upper limit of normal thyroid volume of children at the age of 8 - 10 years old in a province was reasonable, and these normative values were useful for the IDD surveillance in a province and were also referential for revision of Chinese national normative values for schoolchildren. 2. HVI maybe the best method to adjust the thyroid volume at present.