胸腺素促毛囊生长作用研究进展

Thymosin promotes the growth of hair follicles： a review

胸腺素是一类具有多重生物学功能的小分子多肽，普遍存在于各种组织细胞中，在生理和病理活动中起重要作用。胸腺素p4可通过激活毛囊干细胞、促进基质金属蛋白酶-2的合成和分泌及诱导血管生成等方式促进毛囊生长。通过开展相关的基础与临床研究，胸腺素类药物很有希望引入到一些顽固的脱发疾病的治疗中。

Thymosin, a kind of small peptide with multiple biologic functions, is widely distributed in cell of various tissues. It plays an important role in physiological and pathological activities. Thymosin beta4 can promote the growth of hair follicles via activating hair follicle stem cells, increasing matrix metalloproteinase-2 production and secretion, inducing blood vessel formation, and so on. Thymosin is expected to be introduced into the treatment of obstinate hair loss through a series of pertinent basic and clinical studies.