高尿酸血症与原发性高血压关系探讨

Relationship Between Hyperuricemia and Primary Hypertension

目的探讨高尿酸血症与原发性高血压病关系。方法比较高血压组112例患者与正常血压组120例之间的血尿酸水平,分析高尿酸血症与原发性高血压之间的关系。结果高血压病组血尿酸为(471.88±36.47)μmol/L,正常血压组血尿酸为(268±12.36)μmol/L,两者之间差异有统计学意义(P<0.01)。血尿酸水平随着高血压病分级程度及危险度增大而增加(P<0.05)。结论血尿酸水平与高血压病关系密切,高尿酸血症可能是高血压病独立危险因素,是导致心、脑、肾损害的重要因素之一。

Objective To study the relationship between hypemricemia and primary hypertension. Method The level of serum uric acid in hypertension group （112 cases）and control group （120 cases）was compared, and the relation ship between high serum uric acid and primary hypertension was analyzed. Results The mean level of serum uric acid in hypertension group was（471.88 ±36.47）μmol/L, and in the controU group it was（268±12.36）μmol/L. The statistical difference was significant （P 〈0. 01 ）. The level of serum uric acid increased with the increase of grading and the risk of hypertension （P 〈 0.05）. Conclusion Serum uric acid and hypertension are related closely. Hyperuricemia is possibly an independent risk factor of hypertension which can cause injury to heart, brain or kidney.