摘要
急性缺血性卒中是导致老年人残疾和死亡的一种重要疾病。及时和有效的治疗是提高患者生活质量的关键，其中又以急性期溶栓治疗最为重要。本文对溶栓治疗的时间窗、病例和溶栓药物的选择、溶栓治疗的风险和效益、出血性转化的病理生理学及其预防、高龄和基底动脉闭塞患者的溶栓治疗等最新进展进行综述。
Acute ischemic stroke is an important disease that causes disability and death in the elderly. A prompt and effective therapy is the key for improving the quality of life of patients; however, the most important one is acute thrombolytic therapy. This article reviews the latest advances in time window of thrombolytic therapy, selection of eligible patients and drugs, risk and benefit of thrombolysis, pathophysiology of hemorrhagic transformation, prevention, advanced age and thrombolysis in patients with basilar occlusion.
出处
《国际脑血管病杂志》
2007年第5期387-390,共4页
International Journal of Cerebrovascular Diseases
基金
云南省自然科学基金（2002C0003R）
关键词
缺血性卒中
溶栓疗法
时间窗
灌注加权成像
继发性脑出血
ischemic stroke
thrombolytic therapy
time window
perfusion-weighted imaging
secondary intracerebral hemorrhage
