微量元素锌在骨折愈合过程中的作用

Effect of Trace Element on Serum ALP in the Process of Fracture Healing

目的:通过微量元素锌对血清碱性磷酸酶(ALP)的影响,探讨其促进骨痂形成及骨折愈合的作用。方法:将86例创伤性骨折患者随机分为A组(常规治疗组)及B组(常规治疗+口服锌制剂组),每组43例。分别于术后第1、3、5周行X线及ALP检查,观察骨折愈合情况及ALP含量。结果:X线观察显示,在第3、5周B组的骨膜反应、骨痂形成均比A组明显,差异有显著性(P(0.01);B组ALP含量在术后第1、3、5周均明显高于A组。结论:微量元素锌可活化ALP及促进骨痂钙盐的沉积,对骨折愈合有明显促进作用。

Objective： The aim of study was to discusses the effect of trace element （zinc） on promoting the fracture healing through influencing serum alkaline phosphatase levels（ALP）. Methods：86 fracture patients were divided into two groups：A group （conventional treatment group）and B group（ conventional treatment ＋ take orally zinc preparation group） ,Each group had 43 patients. All the patients received X-ray check and serum ALT measure at l st,3rd and 5th weeks after operation. Results： X-ray check showed the periosteal reaction,callus formation were better in A group that in B group （P 〈 0, 01 ） the level of serum ALP in B group were higher than those in A group at 1 st ,3rd,Sth weeks after operation, Conclusion：The trace element （zinc） has an obvious promoter action for fracture healing,may activate the serum ALP and the promote callus caIcium salt deposition.