干香柏的化学成分研究

Studies on the Chemical Constituents from the Branches and Leaves of Cupressus duolouxiana

目的:研究我国特有柏科植物干香柏(Cupressus duolouxianaHickel)的化学成分,为阐明其有效成分提供依据。方法:利用各种色谱技术进行分离,根据化合物的光谱数据和理化常数鉴定其结构。结果:从干香柏枝叶的乙醇提取物中分离得到6个化合物,分别是(7S,8S)-3-甲氧基-3′,7-环氧-8,4′-氧化新木脂素-4,9,9′-三醇((7S,8S)-3-methoxy-3′,7-epoxy-8,4′-oxyneoligna-4,9,9′-triol,Ⅰ),山柰素(kaempferol,Ⅱ),槲皮素(quercetin,Ⅲ),胡桃宁(juglanin,Ⅳ),槲皮素-3′-甲氧基-3-O-α-L-阿拉伯呋喃糖苷(quercetin-3′-methoxy-3-O-α-L-arabinofuranoside,Ⅴ)和槲皮素-3-O-α-L-阿拉伯呋喃糖苷(avicularin,Ⅵ)。结论:所有化合物均为首次从该植物中分离得到。

Objective ： To investigte the chemical constituents from the branches and leaves of Cupressus duolouxiana native to China in order to obtain a more comprehensive understanding of its effective components. Methods ： Compounds were isolated and purified by silica gel column chromatography. They were identified and structurally elucidated by spectral analysis. Results： Six compounds were isolated from the ethanolic extracts of Cupressus duolouxiana, which were identified as （7S,8S） -3-methoxy-3＇ ,7-epoxy-8,4＇-oxyneoligna-4,9,9 ＇-triol （Ⅰ）, kaempferol （Ⅱ）, quercetin （ Ⅲ）, juglanin （Ⅳ）, quercetin-3＇-methoxy-3-O-α-L-arabinofuranoside （ Ⅴ） and avicularin（Ⅵ）. Conclusion： All compounds are obtained from this plant for the first time.