摘要
目的:对大川芎方治疗偏头痛效应组分的提取、纯化工艺进行研究。方法:采用单因素及正交试验设计分别考察了川芎中含阿魏酸效应组分、天麻中含天麻素效应组分的提取、纯化工艺,并用药理实验评价其药理效应。结果:含阿魏酸效应组分的出膏率为1.67%,其中阿魏酸含量为5.82%;含天麻素效应组分的出膏率为5.38%,其中天麻素含量为8.45%。结论:大川芎方治疗偏头痛的效应组分得到有效的提取、纯化,且工艺简单、稳定。
Objective: To study on the process of extraction and purification of active parts from Da Chuan Xiong Fang for treatment of migraine. Methods : the process of extraction and purification of active parts with ferulic acid and gastrodin were optimized respectively by direct comparison and orthogonal design. ReSults: Paste rate of active parts with ferulic acid was. 1.67% and the content of ferulic acid was 5.82%. Paste rate of active parts with gastrodin was 5.38% and the content of gastrodin was 8.45%. Conclusion: Active parts from Da Chuan Xiong Fang for treatment of migraine are extracted and purified effectively.
出处
《中药材》
CAS
CSCD
北大核心
2007年第6期721-723,共3页
Journal of Chinese Medicinal Materials
基金
上海市重点学科建设项目资助(项目编号:T0301)
关键词
大川芎方
效应组分
提取
纯化
Da Chuan Xiong Fang
Active parts
Extraction
Purification