颈动脉粥样硬化与冠心病相关性临床研究

The Clinical Research of Relationship between Carotid Artery Atherosalerosis and Coronary Heart Disease

目的研究颈动脉粥样硬化与冠心病的相关性。方法应用彩色多普勒超声诊断仪观察63例冠心病患者及30例健康对照者颈动脉结构、IMT及斑块形成情况。结果(1)IMT在冠心病组明显高于对照组(P<0.05);(2)心肌梗死组IMT及斑块发生率较心绞痛组有明显增高趋势,但无显著统计学意义(P>0.05);(3)冠状动脉造影阳性者颈动脉斑块积分显著高于冠状动脉造影阴性者(P<0.05),且与冠脉病变支数呈显著正相关(r=0.623)。结论颈动脉IMT的增厚与冠心病的发生有着密切联系,监测颈动脉斑块总积分可在一定程度上反映冠状动脉硬化情况。

Objective To explore the correlation between carotid artery atherosalerosis and CHD. Methods Color doppler flow imaging was employed to observe carotid artery structure, IMT and plaque in 63 patients with CHD and 30 control subjects. Results （1）IMT appears significant increased in CHD group as compared with in control group.（2）The IMT and morbidity of plaques were larger in myocardial infarction group than angina group, but no significant deference. （3）The positive cases in coronaryarteriography have significant high plaque score as compare with the negative cases,and also vetated to the amount of involved branches of carotid artery. Conclusion The thickness of carotid artery has close relation to CHD,Monitoring the plaque of carotid artery can show the condition of CHD in some extent.