摘要
[目的]了解不动杆菌的感染及耐药情况,为临床合理用药提供依据。[方法]按革兰阴性杆菌的临床常规鉴定方法,用K-B法对16种抗生素的药敏进行测定。[结果]在分离的45株不动杆菌中以洛菲不动杆菌为主,占51.1%,其次为醋酸钙不动杆菌,占35.6%。临床分离出的不动杆菌主要来源于痰标本(71.1%)。药敏结果显示,不动杆菌对亚胺培南最为敏感(89.7%),其次为头孢他啶/克拉维酸(64.4%)、头孢噻肟/克拉维酸(64.4%)。[结论]不动杆菌的耐药谱广,且有多重耐药现象。临床医师必须遵守抗生素使用原则,严格掌握其适应证,合理使用抗生素,控制和预防耐药菌感染的发生和流行。
[Objective] To study the situation of infection and drug resistance of Acinetobacter, and provide basis for clinical medicine administration. [Methods] Indentification of strains of Gram-negative bacteria was carried out by the conventional biochemical assay, and susceptibility test of 16 kinds of antibiotics was done by Kirby-bauer method. [ Results] Of the 45 isolated strains of Acinetobacter, A. lowffi accouted for 51.1%, which was followed by A. calcoaceticus, accouting for 35.6%. Acinetobacter were mainly isolated from sputum samples. The susceptibility tests showed that the antibiotics sensitive to Acinetobacter were Imipenem （89.7%）, Ceftazidime/Clavulanic Acid （64.4%） and Cefotaxime/Clavulanie Acid （64.4%） in sequence. [Conclusions] Acinetobacter show resistance to many drugs, and they are multiple antibiotic resistance. Clinicians must use antibiotics properly to control and prevent infection of drug-resistance bacterium.
出处
《现代预防医学》
CAS
北大核心
2007年第14期2783-2784,共2页
Modern Preventive Medicine
关键词
不动杆菌
感染
耐药性
Acinetobacter
Infection
Drug resistance
