心电图T波与QT离散度判断急性心肌梗死静脉溶栓疗效的意义

The Value of T Wave and QTd in Evaluating the Effectiveness of thrombolysis in Acute Myocardial Infarction

目的:观察急性心肌梗死(AMI)行尿激酶静脉溶栓治疗后,心电图T波及QT离散度(QTd)变化对判断冠状动脉(冠脉)再灌注的价值。方法:56例AMI采用尿激酶静脉溶栓治疗,分析溶栓后24小时内T波倒置情况及溶栓前后QTd变化。结果:溶栓后24小时内T波倒置组冠脉再灌注率62.7%,未倒置组冠脉再灌注率31.6%,两组比较有极显著性差异(P<0.01);溶栓成功组QTd与溶栓前及失败组比较,显著缩短(P<0.01)。结论:AMI静脉溶栓后24小时内T波倒置及QTd明显缩短可作为冠脉再灌注的重要观察指标。

Objective：To investigate the changes of T Wave and QTd in evaluating reopening of coronary artery after dissolving thrombus with urokinase in acute myocardial infarction（AMI）. Methods：56 patients with AMI received urokinase intravenously for dissolving thrombus. The changes of T waves and QTd were observed in 24 hrs after treatment. Results：The reopening rate of coronary artery in patients with inverted T waves was 62.7% , the reopening rate of coronary artery in patients with no inverted T waves was 31.6% , there was significant difference between them（P 〈 ）. Compared to patients with failed thrombolysis, QTd was shorten after thrombus dissolving in patients with successful thrombolysis （P 〈 0. 01 ）. Conclusion：After thrombolysis treatment, inverted T waves and shortened QTd can be considered as two important indexes suggesting reopening of coronary artery in AMI.