联用低分子右旋糖酐和川芎嗪治疗肺原性心脏病急性发作期50例疗效观察

Observation on therapeutic effect of dextran40 and ligustilide in treating 50 cases of acute episodewith cor pulmonale

目的：观察静脉联用低分子右旋糖酐和川芎嗪治疗肺原性心脏病（肺心病）急性发作期的疗效。方法：选择对照组（常规治疗组）及治疗组（联用低分子右旋糖酐和川芎嗪）各５０例患者进行治疗和观察。于治疗后２周测定血液流变学变化并作疗效判断。结果：治疗组临床表现改善程度优于对照组（Ｐ＜０．０５）；治疗组２周后血液流变学参数明显降低（Ｐ＜０．０５），而对照组则无明显变化（Ｐ＞０．０５）。结论：肺心病急性发作期联用低分子右旋糖酐和川芎嗪治疗安全且效果显著。

Objective:To observe the therapeutic effect of dextran40 intravenously add to “chuan xiong qin” on acute episode with cor pulmonale.Methods:50 cases were treated with conventional therapy (control group) and 50 cases were treated with dextran40 add to “chuan xiong qin” on the basis of routine therapy(treatment group).The hemorrheologic examination was made after two weeks.Results:The improvement of clinical condition was superior in the treatment group to control group( P <0 05).The hemorrheologic parameters were decreased obviously after two weeks in the treatment group,while it was no change in the control group.Conclusions:These data showed that dextran40 add to “chuan xiong qin” are benefit and safe for treating acute episode with cor pulmonale.