小儿肺炎支原体感染肺外并发症临床特征(附521例分析)

Clinical Character of Extra-pulmonary Complication following Mycoplasma Pneumoniae Fection:Clinical Analysis of 521 Cases

目的:了解小儿肺炎支原体(mycoplasma pneumoniae,MP)感染肺外并发症的临床特征。方法:对521例经ELISA方法检测MP-IgM≥1:80、冷凝集试验≥1:32确诊为MP感染者临床资料进行回顾性分析。结果:521例均有呼吸道症状,334例以呼吸道症状为主(64.1%),187例(35.9%)有肺外并发症,以消化、皮肤黏膜及淋巴结、心血管、泌尿、血液及神经等系统多见。142例因肺外脏器受累,在病程早期曾误诊,误诊率27.3%。521例全部经大环内酯类抗生素规则治疗痊愈。结论:MP感染可引起多系统、多脏器损害,应引起临床重视。

Objective：To study the clinical character of extra pulmonary complications following mycoplasma pneumoniae infection. Methods ：The clinical data of 521 patients with MP infection who were diagnosed by ELISA （MP IgM ≥ 1： 80） and cold agglutionation test（ 〉 1： 32） was analyzed retrospectively. Results： All patients had respiratory symptoms. There were extrapulmonary complications in 187 patients （35.9%） involved digestion system, skin and m ucosa, lymph node, cardiovascular system, urinnary system, haematological system and neural system. 142 patients with extrapulmonary complications were misdiagnosed during earlier course of disease, the percentage of misdiagnosis was 27.3%. All patients had been improved after received macrolide drugs. Conclusion：MP infection can damage multi systems and organs. We should pay attention to it.