食管癌术后早期不同途径营养支持的疗效比较

A comparative study of postoperative early nutritional supports in esophageal carcino- ma patient

50例食管癌手术病人随机分成两组 :肠内营养组 ( EN组 ) 2 7例 ;肠外营养组 ( PN组 ) 2 3例。两组自术后第 1d起 ,给予等氮量、等热能的营养支持 ,连续 8d。监测营养过程中体重、血浆蛋白、免疫指标及氮平衡。结果表明 :体重、血浆蛋白变化两组差异不明显。两组术后第 8天达正氮平衡 ,CD4 +和 CD4 +/CD8+比值明显升高 ,NK细胞活性明显增强 ,组间比较 ,也无明显差异。结论 :两种营养方式对食管癌术后营养支持效果均满意。与 PN相比 ,EN具有更符合生理需求。

Fifty postoperative patients who suf- fered esophageal carcinoma were divided randomly into two groups.They received either enteral nutrition(Group EN,n=2 7) or parenteral nutrilion(Group PN,n=2 3) . The provisions of calorie and nitrogen were equal in the two groups.Nutrition support was started on the first postoperative day and continued for8days.The weight plas- ma proteins,immunological parameters and nitrogen balance were evaluated.The re- sults showed that there was no significant difference in body weight and serum albu- min level between the two groups.The pos- itive nitrogen balance were reached in both groups on the8th day.The CD4+percents age,the ratio of CD4+/ CD8+and NK cell activity were elevated,The conclusion is that the values of both EN and PN are sati- factory.In contrast with PN,EN has the advantages of physiological concordance and low cost.