摘要
目的:观察石棉纤维对肺泡巨噬细胞作用时间和剂量生物学效应关系。方法:采用细胞体外培育。结果:细胞崩解率、乳酸脱氢酶活性随孵育时间和剂量增加而增加;细胞内钾离子浓度随时间和剂量增加而降低。结论:结果显示石棉纤维具有明显的细胞毒性作用。
Objective:Aim of this experimental study was to observe the time dose biological effect on guinea pig macrophages.Methods:Used a experimental method on macrophages in vitro.Results:The cytoclosis percent and lactate dehydrogenase increased a long with culture time and asbestos fiber dose increased but potassium ion (K +) concentration reduced.Conclusion:The experimental result indicated that asbestos fiber possess a notable cytotoxic effect.
出处
《河南医学研究》
CAS
1997年第2期128-130,共3页
Henan Medical Research
基金
河南省医学科学院科研基金