肝脾动脉联合栓塞治疗原发性肝癌并脾功能亢进的临床分析

Clinical Analysis of TACE Combined with PSE Treating Hepatocellular Carcinoma with Hypersplenism

目的探讨肝脾动脉联合栓塞治疗原发性肝癌合并脾亢的临床价值和并发症。方法采用肝动脉栓塞术(TACE)联合部分脾栓塞(PSE)治疗原发性肝癌合并脾亢患者37例,观察术后瘤体缩小程度和脾亢缓解情况及并发症。结果肝癌瘤体缩小有效率为70.3%;治疗后两周,脾亢缓解有效率为89.2%;治疗后1月,脾亢缓解有效率为78.4%,未发生脾脓肿等严重并发症。结论TACE联合PSE是治疗原发性肝癌合并脾亢安全、有效的方法。

Objective To observe clinical value and complication of treatment primary hepatocelluar carcinoma （HCC） with hypersplenism by using transcatheter arterial chemombolization （TACE） combined with partial splenic embolization （PSE）. Methods 37 patients with hypersplenism were treated by TACE and PSE to observe the degree for reduction of tumor volume and remission of hypersplenism and incidence of complications, Results Tumor reduction rate of HCC patients was 70. 3%. After treating two weeks and one month, the emission rate of hypersplenism patients was 89. 2% and 78. 4% respectively. There was no severe complication such as hypatic abscess. Conclusion TACE combined with PSE is a safe and effective method to treat HCC with hypersplenism.