1280株常见病原菌的分布及耐药分析

Distrbution and Drug Resistance Analysis for 1280 Strains of Pathogens

目的:通过分析病原菌的耐药性,为临床合理用药及控制细菌耐药性的发展提供参考。方法:细菌鉴定用VITEK-32全自动微生物分析系统及常规法鉴定。药敏试验采用K-B纸片扩散法。结果:分离的病原菌有以下特点:①革兰阴性杆菌分离率明显高于革兰阳性球菌。②耐甲氧西林葡萄球菌百分比增高。③肠杆菌属、枸橼杆菌属、变形杆菌属、铜绿假单胞菌耐药率明显增高。结论:病原菌对常用的抗生素产生程度不等的耐药性,临床应及时掌握病原菌对抗生素耐药的新动态。

Objective：To investigate the distribution and drug Resistance analysis of pathogens and provide useful information for the clinical treatment. Methods ： Strains were identified by VITEK - 32 automated microbe system Among and classical methods. The drug resistance were measured by standard K - B assay methods. Results ： ① 1280 strains, isolated rate of Gram negative is higher than Gram positive. ②Isolated rate of MRSA is high. ③The rate of resistance to antibiotic of Enterococcus, Citrobacter,Proteus ,P. aeruginosa are high. Conclusions： ：The resistance rates to common antibiotic in pathogens are various degrees, clinical physicians should select antimicrobial carefully and understand trend of pathogens resistance to antibiotics in time.