膀胱癌造口病人生存质量及其影响因素的研究

A study on quality of life of bladder carcinoma patients undergoing neostomy and its influencing factors

[目的]了解膀胱癌造口病人术后12个月内生存质量状况及其影响因素。[方法]选择36例膀胱癌腹壁造口病人作为造口组及同期膀胱癌行保留膀胱手术病人36例作为对照组,分别在术后1个月内、3个月、6个月和12个月,采用世界卫生组织生存质量(WHOQOL-100)量表收集资料;选择欧洲癌症研究与治疗组织直肠癌特异量表(QLQ-CR38)对造口组病人进行上述4个时间段生存质量调查。[结果]造口组与对照组WHO-QOL-100得分术后1个月内差异无统计学意义(P>0.05),在术后3个月有了明显改善;造口组病人QLQ-CR38中身体形象、泌尿道症状和与造口相关问题,术后3个月后有明显改善。[结论]膀胱癌造口病人术后1年内的生活质量是动态变化的,而且生存质量较未造口病人差,与造口相关的问题对造口病人的生存质量影响较大。

Objective： To know about the quality of life of bladder carcinoma patients who had undergone enterostomy within 12 months after operation and its influencing factors. Methods： A total of 36 bladder carcinoma patients who had undergone enterostomy in abdominal wall were selected as enterostomy group. Another 36 homeochronous bladder carcinoma patients who underwent reserving bladder operation were as control group. Data of all cases were collected by adopting world health organization quality of life scale （WHOQOL- 100） and they were followed up at 1 month, 3 months, 6 months and 12 months respectively. By using European cancer study and treatment organization for rectal cancer specific scale （QLQ-CR38）, the quality of life of all patients of enterostomy group in above - mentioned the four time points was investigated. Results： There was no statistical significance in terms of scores of .WHOQOL- 100 scale at one mouth after operation between the two groups of cases. The life quality including physical appearance, urinary tract symptom and enterostomy related problems of enterostomy group patients were significantly improved at three months after operation. Conclusion： The quality of life of bladder carcinoma patients undergoing enterostomy enterostomy is changed constantly within one year after operation. The quality of life of them is worse than that of non - enterostomy group patients. Enterostomy related problems have greater influences on the quality of life of these cases.