摘要
Slamon等在1987年通过人乳腺癌的研究,首先报道了原癌基因HER2的扩增,并提示其与肿瘤易复发和预后较差有关。这类肿瘤往往体积较大,患者腋淋巴结常呈阳性,无病生存期较短,对CMF(环磷酰胺、甲氨蝶呤、氟尿嘧啶)化疗可能耐药,对蒽环类药物敏感,其中约50%雌激素受体(ER)阴性。
出处
《中华外科杂志》
CAS
CSCD
北大核心
2007年第13期889-890,共2页
Chinese Journal of Surgery
同被引文献12
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二级引证文献5
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1邓晓莉,李建一,张文海.MMP-2和MMP-13与乳腺癌腋窝淋巴结转移的相关性[J].中华内分泌外科杂志,2011,5(6):365-369. 被引量:3
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2孙丹丹,王颖梅,张慧英,赵敬,马学功,薛凤霞.子宫内膜癌雄激素受体表达及临床意义[J].实用妇产科杂志,2012,28(2):131-134. 被引量:8
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3吴晶晶,陈曦.乳腺癌相关雄激素受体的研究进展[J].临床肿瘤学杂志,2014,19(3):280-283. 被引量:7
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4张小伟,黄必飞,吴爱姣,胡桂女.乳腺浸润性大汗腺癌的临床病理分析[J].中华内分泌外科杂志,2018,12(5):433-434. 被引量:4
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5杨骁,李靖若.雄激素受体与乳腺癌[J].河南医学研究,2019,28(8):1531-1532. 被引量:2
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1马大昌,武力.乳腺癌HER2阳性的分子靶向治疗研究进展[J].中国医师进修杂志,2012,35(9):71-74. 被引量:3
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2廖玲,刘泓基.Syk基因甲基化与HER2基因在胃癌组织表达的研究[J].广东医学,2011,32(5):660-661. 被引量:3
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3冯奉义.化疗在肿瘤治疗中的地位[J].癌症康复,2002(3):19-19.
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4岳瑶,李惠平.HER2和AKT与乳腺癌预后研究进展[J].癌症进展,2011,9(3):271-273. 被引量:5
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5程波,仇登波,帅晓明,李治.乳腺癌中HER2基质金属蛋白酶-2和9的表达及其相互关系[J].中华实验外科杂志,2004,21(12):1513-1514. 被引量:9
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6高津,张莉莉,胡赛男,袁渊.HER2表达强度对三阴性乳腺癌无病生存率的影响[J].癌症进展,2016,14(12):1221-1224. 被引量:3
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7张斌明,盛志娟,姜专基,宋波,郭雁翔,高波,姜晓燕,白晓蓉.老年乳腺癌新辅助内分泌治疗与新辅助化疗的疗效观察[J].甘肃医药,2016,35(12):907-909. 被引量:1
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8刘冀龙.老年人胃癌组织中HER2的表达及其临床意义[J].中国医药导刊,2012,14(8):1349-1350. 被引量:4
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9王晓东,杨金巧.腋淋巴结阳性乳腺癌MMP-2的表达及预后[J].华西医学,2002,17(2):176-177.
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10陈晓钟,范云,陈秀勇,张鸿未.46例乳癌脑转移的治疗及预后分析[J].中华放射肿瘤学杂志,1994,3(4):239-240. 被引量:2