期刊文献+

胃癌细胞周期异常和DPC4基因的关系 被引量:1

原文传递
导出
摘要 细胞周期异常是胃癌发生、发展过程中的主要表现,抑癌基因DPC4的失活或缺失使其不能发挥抑制肿瘤过度增殖的作用。我们通过检测胃癌组织的DPC4mRNA水平和胃癌组织的细胞周期各项指数来探讨两者间的关系。
出处 《中华外科杂志》 CAS CSCD 北大核心 2007年第13期924-925,共2页 Chinese Journal of Surgery
基金 山东省科技厅资助项目(2003-23)
  • 相关文献

参考文献4

  • 1Hahn SA, Schutte M, Hoque AT, et al. DPCA, a candidate tumor suppressor gene at human chromosome 18q21.1. Science, 1996, 271:350-353.
  • 2Nishizuka S, Tamura G, Maesawa C, et al. Analysis of the DPC4 gene in gastric carcinoma. Jpn J Cancer Res, 1997,88:335-339.
  • 3Xiangming C, Natsugoe S, Takao S, et al. Preserved Smad4 expression in the transforming growth factor beta signaling pathway is a favorable prognostic factor in patients with advanced gastric cancer. Clin Cancer Res, 2001,7: 277-282.
  • 4Dai JL, Bansal RK, Kern SE. G1 cell cycle arrest and apoptosis induction by nuclear Smad4/Dpc4: phenotypes reversed by a tumorigenic mutation. Proc Natl Acad Sci USA, 1999, 96:1427- 1432.

同被引文献8

  • 1Dicken B J,Big am DL,Cass C,et al.Gastric adenocarcinoma:review and considerations for future directions.Ann Surg,2005,241 (1):27 -39.
  • 2Yoshikawa T,Sasako M,Yamamoto S,et al.Phase Ⅱ study of neoadjuvant chemotherapy and extended surgery for locally advanced gastric cancer.Br J Surg,2009,96(9):1015 -1022.
  • 3Charfare H,Limongelli S,Purushotham AD.Neoadjuvant chemotherapy in breast cancer.Br J Surg,2005,92(1):14 -23.
  • 4Kim DY,Kim JH,Lee SH,et al.Phase Ⅱ study of oxaliplatin,5-fluorouracil and leucovorin in previously platinum-treated patients with advanced gastric cancer.Ann Oncol,2003,14(3):383 -387.
  • 5Sumpter K,Harper-Wynne C,Cunning ham D,et al.Report of two protocol planned interim analyses in a randomised multicentre phase Ⅲ study comparing capecitabine with fluorouracil and oxaliplatin with cisplatin in patients with advanced oesophagogastric cancer receiving ECF.Br J Cancer,2005,92(11):1976-1983.
  • 6Cascinu S,Graziano F,Catalano V,et al.Prognostic value of Sphase fraction in T3NOMO gastric cancer.Implications for adjuvant chemotherapy.Anticancer Res,2000,20(5C):3839-3842.
  • 7张军,张菁,孟化,吴国聪,蔡军,王康里,张忠涛,王宇.改良FOLFOX7方案新辅助化疗对进展期胃癌患者的疗效分析[J].中华消化外科杂志,2009,8(6):416-418. 被引量:18
  • 8金懋林,陈强,程凤歧,陈伟,陈黎,潘良熹,杨宇飞.奥沙利铂联合亚叶酸钙和5-氟尿嘧啶治疗晚期胃癌的研究[J].中华肿瘤杂志,2003,25(2):172-174. 被引量:404

引证文献1

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部